She clocked 50.68 seconds, beating her previous record of 51.41, which she set at the US Championships last month.
McLaughlin’s supreme performance marked a record-breaking run for the American over the past year.
She ran an astonishing 51.90 seconds in the 400m hurdles at the US Olympic trials last summer, according to the World Athletics website.
McLaughlin then set another world record and won gold with a run of 51.46 seconds at the Tokyo 2020 Olympics.
‘Faster and faster’
McLaughlin became the first woman to complete the 400m hurdles in under 51 seconds.
“I ran the race the way Bobby (Kersee, his trainer) wanted. I knew coming home that if I just kept my cadence and stayed on the stride pattern we could do it and that’s come.
“The level of the 400m hurdles is definitely improving. We have a full group of girls who are ready to push their bodies to the next level and we are seeing the times drop,” added McLaughlin.
“She was so up front at the end, so I was always doubting if I really had a good race because it was very good. Then I saw the time and I was like, ‘Wow.’ It’s amazing to be part of it and to finish second in such a race,” added Bol.
Muhammad, who won silver in the same event at Tokyo 2020, said she had “mixed emotions” about her performance.
“It’s great to get a medal, but I came into these championships with the strength of having always medaled in all the championships, despite all the injuries. But as a competitor, you always want more .”